SCHEMBL14625641 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	GAA	P10253	1/20	0.37

▸	LMNA	P02545	2/20	0.36

▸	TSHR	P16473	1/20	0.36

▸	TACR1	P25103	4/20	0.35

▸	POLB	P06746	1/20	0.34

▸	CNR1	P21554	1/20	0.34

▸	TP53	P04637	1/20	0.34

▸	MAPT	P10636	1/20	0.34

▸	PDE3B	Q13370	1/20	0.34

▸	PDE3A	Q14432	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	TIPARP	Q7Z3E1	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4183677	0.84	TACR1 (0.40)	GAALMNATSHRTACR1TP53
SCHEMBL4179242	0.72	PDE3B (0.41)	GAATACR1PDE3BPDE3AALDH1A1
SCHEMBL4169497	0.70	AR (0.38)	GAALMNATSHRTACR1POLB
SCHEMBL4169501	0.70	AR (0.38)	GAALMNATSHRTACR1POLB
SCHEMBL4182274	0.61	AR (0.41)	TSHRMAPTALDH1A1SMN1; SMN2KMT2A
SCHEMBL10722317	0.58	GAA (0.62)	GAALMNAALDH1A1KMT2A
SCHEMBL9565826	0.58	LMNA (0.55)	LMNATSHRMAPTALDH1A1KMT2A
SCHEMBL23537676	0.56	AR (0.40)	—
SCHEMBL10008214	0.56	GAA (1.00)	GAALMNATSHRPOLBALDH1A1
SCHEMBL11932402	0.55	GAA (0.85)	GAALMNAPOLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007005887-A2	ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF	LIGAND PHARMACEUTICALS INCORPORATED (US)	2007-01-11	—	—	WO	disclosed