Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741030 | 0.86 | CYP1A2 (0.46) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL12561078 | 0.86 | CYP1A2 (0.46) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL14535117 | 0.84 | SMN1; SMN2 (0.38) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL13070934 | 0.82 | CASP1 (0.44) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL14228220 | 0.82 | CYP1A2 (0.48) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL13427300 | 0.82 | CYP1A2 (0.48) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL8198317 | 0.81 | AVPR2 (0.38) | SMN1; SMN2CYP2D6CASP1LMNACXCL8 | |
| SCHEMBL12561103 | 0.80 | CASP1 (0.41) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL13871693 | 0.80 | CASP1 (0.41) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL15078598 | 0.77 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002906-A1 | METHODS AND DOSAGE FORMS FOR REDUCING SIDE EFFECTS OF CARBAMATE COMPOUNDS | ALZA CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |