Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590676 | 0.80 | NOTUM (0.68) | ACHERAB9ANOTUM | |
| SCHEMBL14626154 | 0.79 | NOTUM (0.57) | NOTUM | |
| SCHEMBL14625869 | 0.75 | HRH3 (0.43) | — | |
| SCHEMBL14626056 | 0.74 | AOC3 (0.47) | RAB9ANOTUM | |
| SCHEMBL16494823 | 0.74 | ACHE (0.55) | ACHEBCHE | |
| SCHEMBL14626226 | 0.74 | APEX1 (0.44) | RAB9A | |
| SCHEMBL14626053 | 0.73 | HTR2C (0.45) | NOTUM | |
| SCHEMBL8845729 | 0.72 | HDAC1 (0.44) | ACHEBCHERAB9ALMNA | |
| SCHEMBL1177381 | 0.71 | HSD17B10 (0.58) | NOTUM | |
| SCHEMBL10267244 | 0.70 | NOTUM (0.54) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |