Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222295 | 0.83 | DPP4 (0.52) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL25615427 | 0.83 | DPP4 (0.52) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL14596990 | 0.82 | DPP4 (0.48) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL13162856 | 0.82 | HRH3 (0.62) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL2695269 | 0.80 | DPP4 (0.53) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL23320315 | 0.79 | HRH3 (0.66) | HRH3KCNH2 | |
| SCHEMBL14067198 | 0.79 | DPP4 (0.51) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL2585221 | 0.79 | DPP4 (0.52) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL12390482 | 0.78 | SIGMAR1 (0.56) | DPP4DPP9DPP8HRH3HSD11B1 | |
| SCHEMBL5529166 | 0.78 | DPP4 (0.47) | DPP4DPP9DPP8HRH3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |