SCHEMBL14626194

SCHEMBL14626194

Nc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 20/20 0.78
▸ POT1 Q9NUX5 3/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13989204 0.88 TERT (0.77) TERTPOT1
SCHEMBL13989206 0.88 TERT (0.77) TERTPOT1
SCHEMBL14355589 0.88 TERT (1.00) TERTPOT1
SCHEMBL14355607 0.87 TERT (1.00) TERTPOT1
SCHEMBL14355659 0.86 TERT (0.81) TERTPOT1
SCHEMBL13989207 0.85 TERT (1.00) TERTPOT1
SCHEMBL14355616 0.84 TERT (1.00) TERT
SCHEMBL14355576 0.84 TERT (1.00) TERT
SCHEMBL5335934 0.84 TERT (0.72) TERTPOT1
SCHEMBL14355614 0.84 TERT (1.00) TERTPOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
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