Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2697740 | 0.79 | CYP1A2 (0.55) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL25690608 | 0.77 | CYP1A2 (0.84) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL499818 | 0.77 | CYP1A2 (0.84) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL28562135 | 0.77 | CYP1A2 (0.84) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL31258922 | 0.77 | CYP1A2 (0.84) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL2696608 | 0.77 | SLC6A2 (0.56) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL78821 | 0.76 | CYP2C9 (0.68) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL38819 | 0.76 | CYP2C9 (0.68) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29570568 | 0.76 | CYP2C9 (0.68) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29567211 | 0.76 | CYP2C9 (0.68) | CYP2C9CYP1A2CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7164014-B2 | Protected linker compounds | LINDEN TECHNOLOGIES, INC. (US) | 2007-01-16 | — | — | US | disclosed |