Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258922 | 1.00 | CYP1A2 (0.84) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL25690608 | 1.00 | CYP1A2 (0.84) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL28562135 | 1.00 | CYP1A2 (0.84) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3660587 | 0.92 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL21640458 | 0.90 | CYP1A2 (0.91) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL5052647 | 0.85 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL38819 | 0.85 | CYP2C9 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29402853 | 0.85 | CYP2C9 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL78821 | 0.85 | CYP2C9 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL29567211 | 0.85 | CYP2C9 (0.68) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812421-B9 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-09-25 | — | — | EP | disclosed |
| EP-1812421-B1 | ANTHRANILAMIDE INSECTICIDES | DU PONT (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2564706-A1 | Anthranilamide insecticides | E. I. du Pont de Nemours and Company (US) | 2013-03-06 | — | — | EP | disclosed |
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106075-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | disclosed |
| EP-1802611-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | Syngeta Participations AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006040113-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | C3AR1, C5, C1S | CYP1A2 29/4885CYP2C9 35/4885CYP2C19 371/4885 |
| US-20080275065-A1 | Novel Insecticides | DDT, ACHE, CYP4F11 | CYP1A2 21/4885CYP2C9 51/4885CYP2C19 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.