Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294462 | 0.85 | TLR8 (0.40) | TLR8CASP3SENP8SENP7SENP6 | |
| SCHEMBL14268999 | 0.82 | TLR8 (0.42) | TLR8CASP3SENP8SENP7SENP6 | |
| SCHEMBL14268994 | 0.81 | CASP3 (0.46) | TLR8CASP3SENP8SENP7SENP6 | |
| SCHEMBL14626241 | 0.77 | MAPK13 (0.37) | — | |
| SCHEMBL14625961 | 0.76 | CYP3A4 (0.36) | PDE10A | |
| SCHEMBL4861475 | 0.76 | TLR8 (0.62) | TLR8PDE10A | |
| SCHEMBL14269022 | 0.72 | TLR8 (0.50) | TLR8CASP3SENP8SENP7SENP6 | |
| SCHEMBL14269011 | 0.70 | TLR8 (0.49) | TLR8CASP3SENP8SENP7SENP6 | |
| SCHEMBL24289574 | 0.69 | SSTR2 (0.40) | TLR8 | |
| SCHEMBL27835092 | 0.66 | CASP3 (0.39) | TLR8CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163924-B2 | Ketolide derivatives | CHIRON CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |