Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592611 | 0.84 | KCNJ1 (0.52) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14627092 | 0.84 | EPHX2 (0.41) | MCL1KMT2AMEN1LMNA | |
| SCHEMBL935021 | 0.83 | ALDH1A1 (0.43) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14627093 | 0.83 | ALDH1A1 (0.43) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL933933 | 0.83 | ALDH1A1 (0.40) | KCNJ1KCNH2MCL1KMT2AMEN1 | |
| SCHEMBL16766115 | 0.82 | ALDH1A1 (0.43) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30700623 | 0.82 | ALDH1A1 (0.43) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13437495 | 0.79 | TDP1 (0.41) | KCNH2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL17794171 | 0.78 | CHRNB4 (0.46) | MCL1BCL2MAPTALDH1A1LMNA | |
| SCHEMBL933956 | 0.77 | ALDH1A1 (0.44) | KCNJ1KCNH2KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |