Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.49 |
| ▸ | CHUK | O15111 | 5/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551884 | 0.87 | IKBKB (0.66) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL552143 | 0.83 | IKBKB (0.64) | IKBKBCHUKAURKAFLT3CSNK1E | |
| Trifluoroacetic Acid SCHEMBL551805 | 0.83 | IKBKB (0.62) | IKBKBCHUKAURKAFLT3CSNK1E | |
| Trifluoroacetic Acid SCHEMBL553309 | 0.79 | IKBKB (0.60) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL5023382 | 0.78 | IKBKB (0.56) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL14019062 | 0.78 | IKBKB (0.59) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL14018309 | 0.78 | IKBKB (0.68) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL14626680 | 0.78 | IKBKB (0.54) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL14627025 | 0.74 | IKBKB (0.53) | IKBKBCHUKAURKAFLT3CSNK1E | |
| SCHEMBL14627012 | 0.74 | IKBKB (0.48) | IKBKBCHUKAURKAFLT3CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005534-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |