⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745345 | 1.00 | — | — | |
| SCHEMBL29728550 | 0.90 | LMNA (0.48) | — | |
| Pentabamate SCHEMBL636717 | 0.85 | LMNA (0.44) | — | |
| SCHEMBL29728537 | 0.84 | LMNA (0.40) | — | |
| Methacrylic Acid SCHEMBL21483482 | 0.83 | TDP1 (0.40) | — | |
| SCHEMBL18043494 | 0.82 | — | — | |
| SCHEMBL28623543 | 0.82 | — | — | |
| SCHEMBL8755732 | 0.82 | — | — | |
| SCHEMBL28623541 | 0.82 | — | — | |
| SCHEMBL14592888 | 0.82 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130060013-A1 | Compounds useful for treating neurodegenerative disorders | SATORI PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-7160907-B2 | Pleuromutilin derivatives | SMITHKLINE BEECHAM P.L.C. (GB) | 2007-01-09 | — | — | US | disclosed |