Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480327 | 0.93 | KDM4E (0.40) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1478316 | 0.90 | KDM4E (0.39) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1223300 | 0.84 | KDM4E (0.38) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16076571 | 0.84 | KDM4E (0.38) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1477994 | 0.82 | ABL1 (0.42) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1477905 | 0.82 | KDM4E (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL679753 | 0.82 | KDM4E (0.38) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29769728 | 0.82 | KDM4E (0.38) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11028213 | 0.80 | KDM4E (0.39) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1477857 | 0.80 | KDM4E (0.40) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | claimed |