Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396729 | 0.82 | HSD17B10 (0.54) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL3396733 | 0.82 | HSD17B10 (0.54) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL29804524 | 0.81 | CA12 (0.54) | HSD17B10ALDH1A1HPGDNPC1LMNA | |
| SCHEMBL12156515 | 0.81 | NPC1 (0.69) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL22702112 | 0.81 | CA12 (0.54) | HSD17B10ALDH1A1HPGDNPC1LMNA | |
| SCHEMBL8763794 | 0.81 | ALDH1A1 (0.88) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL29921739 | 0.81 | ALDH1A1 (0.88) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL1591508 | 0.81 | ALDH1A1 (0.88) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL2954316 | 0.81 | HSD17B10 (0.68) | HSD17B10ALDH1A1NPSR1HPGDNPC1 | |
| SCHEMBL22702048 | 0.80 | CA12 (0.56) | HSD17B10ALDH1A1SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | NPY5R, NPY1R, NPY2R | HSD17B10 1161/4885ALDH1A1 4558/4885NPSR1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.