Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627909 | 0.87 | PDK2 (0.51) | PDK2ESR1MEN1KMT2AALOX5 | |
| SCHEMBL16017840 | 0.87 | PDK2 (0.51) | PDK2ESR1MEN1KMT2AALOX5 | |
| SCHEMBL13526106 | 0.86 | ACHE (0.42) | RARARARBRARGAPPPDE4D | |
| SCHEMBL14627892 | 0.81 | ESR1 (0.40) | RARARARBRARGPDK2APP | |
| SCHEMBL16022361 | 0.79 | PDK2 (0.44) | PDK2ESR1MEN1KMT2ACYP3A4 | |
| SCHEMBL13700678 | 0.79 | PDK2 (0.60) | PDK2MMP3ESR1MEN1KMT2A | |
| SCHEMBL21911147 | 0.76 | ESR2 (0.61) | PDK2APPESR1MEN1KMT2A | |
| SCHEMBL26506713 | 0.76 | PDK2 (0.51) | PDK2MMP3 | |
| SCHEMBL13520254 | 0.75 | PDK2 (0.34) | RARARARBRARGPDK2CYP3A4 | |
| SCHEMBL12711690 | 0.73 | ESR1 (0.65) | APPMMP3ESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005289-A1 | MONOMERS AND POLYMERS COMPRISING CONJUGATED GROUPS AND METHODS FOR MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2007-01-11 | — | — | WO | disclosed |