Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628420 | 0.79 | F10 (0.49) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL308289 | 0.79 | F10 (0.49) | TMPRSS11DPRSS1F2F10PLG | |
| Hydrochloric Acid SCHEMBL6544352 | 0.79 | F10 (0.49) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL14628139 | 0.76 | F7 (0.39) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL5497165 | 0.72 | F10 (0.42) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL13283064 | 0.71 | CA12 (0.47) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL13675001 | 0.71 | CA12 (0.40) | TMPRSS11DPRSS1F2F10PLG | |
| SCHEMBL12514665 | 0.69 | F2 (0.46) | TMPRSS11DPLAUF2F10PLG | |
| SCHEMBL8149664 | 0.68 | PRSS1 (0.73) | PRSS1TPSAB1TPSD1TPSG1PLAU | |
| SCHEMBL8346530 | 0.68 | F2 (0.57) | TMPRSS11DPRSS1F2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |