Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 10/20 | 0.38 |
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | TMPRSS11D | O60235 | 5/20 | 0.37 |
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA7 | P43166 | 4/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628420 | 0.79 | F10 (0.49) | F7F10F2TMPRSS11DPLG | |
| SCHEMBL308289 | 0.79 | F10 (0.49) | F7F10F2TMPRSS11DPLG | |
| Hydrochloric Acid SCHEMBL6544352 | 0.79 | F10 (0.49) | F7F10F2TMPRSS11DPLG | |
| SCHEMBL14628024 | 0.76 | TMPRSS11D (0.44) | F10F2TMPRSS11DPLGPRSS1 | |
| SCHEMBL13283064 | 0.75 | CA12 (0.47) | F7F10F2TMPRSS11DPLG | |
| SCHEMBL13675001 | 0.73 | CA12 (0.40) | F10F2TMPRSS11DPLGCA12 | |
| SCHEMBL5494187 | 0.70 | F7 (0.46) | F7F10F2TMPRSS11DPLG | |
| SCHEMBL5497165 | 0.70 | F10 (0.42) | F10F2TMPRSS11DPLGPRSS1 | |
| Hydrochloric Acid SCHEMBL307960 | 0.70 | F7 (0.45) | F7F10F2TMPRSS11DPLG | |
| SCHEMBL8344650 | 0.70 | F2 (0.56) | F10F2TMPRSS11DPLGKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |