Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 5/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631081 | 0.90 | KDM1A (0.63) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585335 | 0.90 | KDM1A (0.54) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14628155 | 0.90 | KDM1A (0.58) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585342 | 0.89 | KDM1A (0.54) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14628243 | 0.89 | KDM1A (0.54) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585311 | 0.89 | KDM1A (0.56) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585299 | 0.89 | KDM1A (0.54) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585303 | 0.88 | RAD52 (0.54) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585340 | 0.87 | KDM1A (0.52) | KDM1AEHMT2ALDH1A1MAPK1RAD52 | |
| SCHEMBL14585316 | 0.87 | KDM1A (0.53) | KDM1AEHMT2ALDH1A1MAPK1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011623-A1 | QUINAZOLINE DERIVATIVES USEFUL IN CANCER TREATMENT | SCHERING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |