⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011163 | 0.85 | — | — | |
| SCHEMBL2077058 | 0.82 | — | — | |
| SCHEMBL8810939 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL8018189 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL8812767 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL8018462 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL8812331 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL16915245 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL16915251 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL2122700 | 0.73 | CES2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190031618-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-31 | — | — | US | claimed |
| US-10118900-B2 | Benzimidazole derivatives useful as CB-1 inverse agonists | JANSSEN PHARMACEUTICA NV (BE) | 2018-11-06 | — | — | US | claimed |
| WO-2017035114-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | WO | claimed |
| US-20170057929-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-02 | — | — | US | claimed |
| CN-102049048-A | Method of treatment or prophylaxis | SPINIFEX PHARM PTY LTD | 2011-05-11 | — | — | CN | claimed |
| US-7608602-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2009-10-27 | — | — | US | claimed |
| CN-101443001-A | Methods of treating or preventing inflammatory pain | UNIV QUEENSLAND (AU) | 2009-05-27 | — | — | CN | claimed |
| EP-1506175-B1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |
| US-20080021208-A1 | Gemcitabine Prodrugs, Pharmaceutical Compositions and Uses Thereof | XENOPORT, INC. (US) | 2008-01-24 | — | — | US | claimed |
| CN-101087619-A | methods of treatment or prevention | UNIV QUEENSLAND (AU) | 2007-12-12 | — | — | CN | claimed |
| US-20040082639-A1 | N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-29 | — | — | US | claimed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | claimed |
| EP-0333174-B1 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-08 | — | — | EP | claimed |
| US-5187156-A | D-Tryptophan- and Phenylalanine-containing tripeptides as tachykinin antagonists; asthma | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| US-5182264-A | Angiotensin II receptor blockers as antiglaucoma agents | SCHERING CORPORATION (US) | 1993-01-26 | — | — | US | claimed |
| EP-0333174-A2 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-20 | — | — | EP | claimed |
| EP-0025897-B1 | PEPTIDES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-03-28 | — | — | EP | claimed |
| US-4420424-A | New peptides and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | claimed |
| EP-0025897-A2 | Peptides and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-01 | — | — | EP | claimed |
| US-4013791-A | MEDICAL DIAGNOSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | claimed |