SCHEMBL14628660

SCHEMBL14628660

CC(=O)[C@@H]1C[C@@H](CO)CN1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 7/20 0.44
ARG1 P05089 1/20 0.41
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP2C19 P33261 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
OGA O60502 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15221802 1.00 DPP4 (0.44) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL14628659 1.00 DPP4 (0.44) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL8294074 0.82 ARG1 (0.40) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL12609037 0.82 ARG1 (0.47) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL3676541 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL1512874 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL3675363 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL4302105 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL1512877 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15
SCHEMBL3675362 0.81 ARG1 (0.59) DPP4ARG1CYP1A2CYP2D6ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 US disclosed
US-20070004646-A1 Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors G.D. SEARLE & CO. (US) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004646-A1 Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors DNPEP, PREP, ANPEP DPP4 105/4885ARG1 2965/4885CYP1A2 3760/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 DPP4 433/4885ARG1 241/4885CYP1A2 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.