SCHEMBL14628813

SCHEMBL14628813

CC(C)C1CC(=O)N(NC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)C1=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
POLB P06746 3/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 1/20 0.35
EZH2 Q15910 1/20 0.35
TP53 P04637 1/20 0.35
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14628814 0.89 GAA (0.39) GAAPOLBTSHRHTTKMT2A
SCHEMBL10583025 0.83 GAA (0.36) GAAPOLBTSHRHTTKMT2A
SCHEMBL9544681 0.79 GAA (0.46) GAAPOLBHTTKMT2AMEN1
SCHEMBL10562354 0.76 GAA (0.38) GAAPOLBHTTKMT2AMEN1
SCHEMBL10562866 0.75 GAA (0.43) GAAPOLBKMT2AMEN1MAPT
SCHEMBL10396993 0.73 GAA (0.43) GAAPOLBHTTKMT2AMEN1
SCHEMBL3295977 0.72 RECQL (0.57) GAAPOLBHTTKMT2AMEN1
SCHEMBL10560570 0.72 GAA (0.43) GAAPOLBKMT2AMEN1MAPT
SCHEMBL10396696 0.72 GAA (0.42) GAAPOLBKMT2AMEN1MAPT
SCHEMBL20043720 0.72 NPC1 (0.36) GAAPOLBMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169835-B2 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-30 US disclosed