Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113757 | 0.74 | — | — | |
| Benzene SCHEMBL27817281 | 0.74 | SMN1; SMN2 (0.53) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Fluoride SCHEMBL14677416 | 0.72 | SMN1; SMN2 (0.50) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Hydrochloric Acid SCHEMBL27533715 | 0.72 | — | — | |
| SCHEMBL11245508 | 0.72 | SMN1; SMN2 (0.50) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL8943068 | 0.70 | MAOA (0.40) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Ethane SCHEMBL11553570 | 0.69 | SMN1; SMN2 (0.47) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Phenol SCHEMBL28851578 | 0.64 | CA12 (0.58) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| Aniline SCHEMBL7770539 | 0.62 | TSHR (0.65) | MAPTSMN1; SMN2HSD17B10MAOAMAOB | |
| SCHEMBL14616136 | 0.62 | TSHR (0.50) | HPGDMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1398027-B1 | Use of matrix metalloproteinase inhibitors for treating or preventing glomerulopathy | SHIONOGI & CO (JP) | 2007-01-10 | — | — | EP | disclosed |