Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947454 | 0.76 | ALDH1A1 (0.43) | RPS6KA5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1996212 | 0.76 | ALDH1A1 (0.43) | RPS6KA5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1997041 | 0.74 | ALDH1A1 (0.45) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL3952706 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL28546795 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27619884 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL5436850 | 0.73 | KDM4D (0.41) | RPS6KA5ALDH1A1CYP3A4MAPTMEN1 | |
| SCHEMBL30523855 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2001316 | 0.72 | RPS6KA5 (0.37) | RPS6KA5KMO | |
| SCHEMBL2269742 | 0.69 | ALDH1A1 (0.48) | RPS6KA5ALDH1A1CYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739081-A1 | HYDRAZINO-SUBSTITUTED HETEROCYCLIC NITRILE COMPOUNDS AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |