Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCK1 | P16333 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460899 | 0.87 | CYP2A6 (0.41) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL1460886 | 0.83 | CYP2A6 (0.35) | CYP2A6CYP1A2TDP1ALDH1A1HSD17B10 | |
| SCHEMBL1443600 | 0.72 | CYP2A6 (0.35) | CYP2A6CYP1A2TDP1 | |
| SCHEMBL667256 | 0.71 | CYP1A2 (0.52) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL819377 | 0.70 | CYP2A6 (0.50) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL8913546 | 0.69 | — | — | |
| SCHEMBL18207370 | 0.68 | CYP1A2 (0.48) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL425085 | 0.65 | CYP1A2 (1.00) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL29399131 | 0.65 | CYP1A2 (1.00) | CYP2A6CYP1A2TDP1MAPTRXFP1 | |
| SCHEMBL819816 | 0.64 | CYP2A6 (0.52) | CYP2A6CYP1A2TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482978-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | The Governors Of The University Of Alberta (CA) | 2012-08-08 | — | — | EP | claimed |
| WO-2011035445-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-03-31 | — | — | WO | claimed |
| EP-2482978-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | The Governors Of The University Of Alberta (CA) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011035445-A1 | HETEROGENEOUS RHODIUM METAL CATALYSTS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2011-03-31 | — | — | WO | disclosed |