Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700587 | 0.79 | HDAC1 (0.38) | HDAC1HDAC6 | |
| SCHEMBL21386534 | 0.79 | HDAC1 (0.33) | HDAC1HDAC6 | |
| SCHEMBL14033017 | 0.76 | NOS3 (0.34) | HDAC1HDAC6 | |
| SCHEMBL30668 | 0.74 | HDAC1 (0.48) | HDAC1HDAC6 | |
| SCHEMBL20076802 | 0.74 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL646972 | 0.73 | TAAR1 (0.38) | — | |
| SCHEMBL8574537 | 0.73 | TAAR1 (0.42) | — | |
| SCHEMBL19512606 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL29605427 | 0.71 | PTGS1 (0.44) | HDAC1HDAC6 | |
| SCHEMBL28773425 | 0.71 | PTGS1 (0.44) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021472-A1 | N-(5-bromo-2-pyridinyl)-(2-4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenylcarboxamide; potent and highly selective inhibitors; coagulation disorders; antithrombotic agents; diagnostic reagents; good bioavailability and/or solubility | MILLENNIUM PHARMACEUTICALS, INC. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021472-A1 | N-(5-bromo-2-pyridinyl)-(2-4-[(2-aminosulfonyl)phenyl]phenylcarbonylamino)phenylcarboxamide; potent and highly selective inhibitors; coagulation disorders; antithrombotic agents; diagnostic reagents; good bioavailability and/or solubility | F2, TFPI, PLG | HDAC1 193/4885HDAC6 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.