Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 4/20 | 0.52 |
| ▸ | LGALS1 | P09382 | 4/20 | 0.52 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.52 |
| ▸ | LGALS7; LGALS7B | P47929 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.41 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848097 | 0.93 | LGALS9 (0.55) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL12847759 | 0.93 | LGALS9 (0.55) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL5974144 | 0.90 | LGALS9 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL7251664 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL16917900 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL1521440 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL8346842 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL16917918 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL8899505 | 0.88 | LGALS9 (0.54) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 | |
| SCHEMBL17193904 | 0.88 | USP2 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605050-B2 | Glycoprotein synthesis and remodeling by enzymatic transglycosylation | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-03-28 | — | — | US | disclosed |
| US-20170081390-A9 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | UNIVERSITY OF MARYLAND, BALTIMORE | 2017-03-23 | — | — | US | disclosed |
| EP-2001358-B1 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | UNIV MARYLAND (US) | 2016-07-13 | — | — | EP | disclosed |
| US-20150087811-A1 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | UNIV MARYLAND (US) | 2015-03-26 | — | — | US | disclosed |
| US-8900826-B2 | Glycoprotein synthesis and remodeling by enzymatic transglycosylation | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-12-02 | — | — | US | disclosed |
| US-20130131325-A1 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-05-23 | — | — | US | disclosed |
| US-8354247-B2 | Glycoprotein synthesis and remodeling by enzymatic transglycosylation | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-01-15 | — | — | US | disclosed |
| US-20110070607-A1 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-24 | — | — | US | disclosed |
| US-7807405-B2 | Drug delivery; drug targetting | UNIVERSITY OF MARYLAND BALTIMORE, OFFICE OF COMMERCIAL VENTURES AND INTELLECTUAL PROPERTY (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2001358-A2 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | University Of Maryland Biotechnology Institute (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20080138855-A1 | Drug delivery; drug targetting | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-06-12 | — | — | US | disclosed |
| WO-2007133855-A2 | GLYCOPROTEIN SYNTHESIS AND REMODELING BY ENZYMATIC TRANSGLYCOSYLATION | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2007-11-22 | — | — | WO | disclosed |