Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600018 | 0.81 | — | — | |
| SCHEMBL14632180 | 0.80 | SMN1; SMN2 (0.31) | SMN1; SMN2TSHRALDH1A1MMP1MMP2 | |
| SCHEMBL942458 | 0.73 | CYP2D6 (0.37) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL13611203 | 0.70 | — | — | |
| SCHEMBL15116682 | 0.70 | — | — | |
| SCHEMBL13554083 | 0.69 | TSHR (0.39) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL17660671 | 0.69 | TSHR (0.39) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL8847013 | 0.65 | — | — | |
| SCHEMBL29042284 | 0.65 | LMNA (0.40) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL29042285 | 0.65 | LMNA (0.40) | TSHRMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169814-B2 | Guanidinium transport reagents and conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-01-30 | — | — | US | disclosed |