SCHEMBL14632136

SCHEMBL14632136

COc1ccc(-c2cc(NCC(O)c3ccccc3)ncn2)cc1.Cc1cccc(-c2cc(NCC(O)c3ccccc3)ncn2)c1.OC(CNc1cc(-c2cccc(OC(F)(F)F)c2)ncn1)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4295390 0.89 FAAH (0.81) FAAH
SCHEMBL3406294 0.85 FAAH (0.78) FAAH
SCHEMBL3403362 0.85 FAAH (0.81) FAAH
SCHEMBL4292272 0.85 FAAH (1.00) FAAH
SCHEMBL13661101 0.85 FAAH (1.00) FAAH
SCHEMBL4292019 0.85 FAAH (1.00) FAAH
SCHEMBL4303928 0.84 FAAH (1.00) FAAH
SCHEMBL4296712 0.84 FAAH (1.00) FAAH
SCHEMBL14632137 0.83 FAAH (0.49) FAAH
SCHEMBL4294760 0.83 FAAH (1.00) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2254415-B1 ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA NV (BE) 2013-01-23 EP claimed