Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632050 | 1.00 | ELANE (0.59) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14632068 | 0.91 | ELANE (0.54) | ELANECYP3A4CYP2C9 | |
| SCHEMBL230899 | 0.88 | ELANE (0.72) | ELANECYP3A4CYP2C9 | |
| SCHEMBL230520 | 0.88 | ELANE (0.72) | ELANECYP3A4CYP2C9 | |
| SCHEMBL1746677 | 0.87 | ELANE (0.58) | ELANECYP3A4CYP2C9 | |
| SCHEMBL232930 | 0.84 | ELANE (0.62) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14632007 | 0.84 | ELANE (0.55) | ELANECYP3A4CYP2C9 | |
| SCHEMBL231686 | 0.84 | ELANE (0.57) | ELANECYP3A4CYP2C9 | |
| SCHEMBL15456300 | 0.84 | ELANE (0.57) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14632131 | 0.83 | ELANE (0.54) | ELANECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |