Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230667 | 0.89 | ELANE (0.70) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632007 | 0.88 | ELANE (0.55) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632131 | 0.87 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632161 | 0.87 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632050 | 0.87 | ELANE (0.59) | ELANECYP2C9CYP3A4 | |
| SCHEMBL229626 | 0.83 | ELANE (0.62) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14647591 | 0.83 | ELANE (0.62) | ELANECYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL229517 | 0.82 | ELANE (0.61) | ELANECYP2C9CYP3A4 | |
| SCHEMBL2742383 | 0.81 | ELANE (0.72) | ELANECYP2C9CYP3A4 | |
| SCHEMBL14632165 | 0.81 | ELANE (0.64) | ELANECYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385945-B1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER IP GMBH (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2385945-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | Bayer Pharma Aktiengesellschaft (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041896-B2 | Virtualization platform with dedicated cache access | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010078953-A1 | TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-07-15 | — | — | WO | disclosed |