Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 1.00 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120911 | 1.00 | SPHK1 (1.00) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20592376 | 1.00 | SPHK1 (1.00) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18194573 | 1.00 | SPHK1 (1.00) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20596127 | 1.00 | SPHK1 (1.00) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23519479 | 0.99 | SPHK1 (0.97) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13896120 | 0.91 | SPHK1 (0.83) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12450365 | 0.88 | SPHK1 (0.79) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13499031 | 0.88 | SPHK1 (0.79) | SPHK1SPHK2 | |
| SCHEMBL20168989 | 0.87 | SPHK1 (0.77) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22861894 | 0.87 | SPHK1 (0.77) | SPHK1SPHK2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4181906-A1 | SPHINGOID COMPOUNDS FOR USE IN PROPHYLAXIS AND/OR THERAPY OF CORONAVIRIDAE INFECTION | Harbins Ruhr Bioscience, Inc. (US) | 2023-05-24 | — | — | EP | claimed |
| WO-2022015348-A1 | SPHINGOID COMPOUNDS FOR USE IN PROPHYLAXIS AND/OR THERAPY OF CORONAVIRIDAE INFECTION | Harbins Ruhr Bioscience, Inc. (US) | 2022-01-20 | — | — | WO | claimed |
| US-12083079-B2 | Sphingoid compounds for prophylaxis and/or therapy of a viral infection | Harbins Ruhr Bioscience, Inc. (US) | 2024-09-10 | — | — | US | disclosed |
| US-11298412-B2 | Sphingoid compounds for prophylaxis and/or therapy of coronaviridae infection | Harbins Ruhr Bioscience, Inc. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20220016222-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF CORONAVIRIDAE INFECTION | Harbins Ruhr Bioscience, Inc. | 2022-01-20 | — | — | US | disclosed |
| US-20200268686-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF A VIRAL INFECTION | Harbins Ruhr Bioscience, Inc. | 2020-08-27 | — | — | US | disclosed |
| US-10688065-B2 | Sphingoid compounds for prophylaxis and/or therapy of a viral infection | Harbins Ruhr Bioscience, Inc. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20200113850-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF A VIRAL INFECTION | Harbins Ruhr Bioscience, Inc. | 2020-04-16 | — | — | US | disclosed |
| US-8591892-B2 | FTY720 increases CD74 expression and sensitizes cancer cells to anti-CD74 antibody-mediated cell death | THE OHIO STATE UNIVERSITY (US) | 2013-11-26 | — | — | US | disclosed |
| US-20130022541-A1 | FTY720 Increases CD74 Expression and Sensitizes Cancer Cells to Anti-CD74 Antibody-Mediated Cell Death | IMMUNOMEDICS, INC. (US) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12083079-B2 | Sphingoid compounds for prophylaxis and/or therapy of a viral infection | SPHK1, SPHK2, S1PR1 | SPHK1 1/4885SPHK2 2/4885CYP3A4 3634/4885 |
| US-20200268686-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF A VIRAL INFECTION | SPHK1, SPHK2, S1PR1 | SPHK1 1/4885SPHK2 2/4885CYP3A4 3634/4885 |
| US-20220016222-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF CORONAVIRIDAE INFECTION | SPHK1, SPHK2, S1PR2 | SPHK1 1/4885SPHK2 2/4885CYP3A4 2358/4885 |
| US-10688065-B2 | Sphingoid compounds for prophylaxis and/or therapy of a viral infection | SPHK1, SPHK2, S1PR1 | SPHK1 1/4885SPHK2 2/4885CYP3A4 3634/4885 |
| US-20200113850-A1 | SPHINGOID COMPOUNDS FOR PROPHYLAXIS AND/OR THERAPY OF A VIRAL INFECTION | SPHK1, SPHK2, S1PR1 | SPHK1 1/4885SPHK2 2/4885CYP3A4 3634/4885 |
| US-11298412-B2 | Sphingoid compounds for prophylaxis and/or therapy of coronaviridae infection | SPHK1, SPHK2, S1PR2 | SPHK1 1/4885SPHK2 2/4885CYP3A4 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.