Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TOP1 | P11387 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28033454 | 0.85 | RAB9A (0.74) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL28221793 | 0.85 | RAB9A (0.74) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL30846536 | 0.85 | NPC1 (0.73) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL29184271 | 0.85 | NPC1 (0.73) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL7153742 | 0.83 | NPC1 (1.00) | NPC1RAB9ABCHEMAPTSMN1; SMN2 | |
| SCHEMBL30461135 | 0.82 | RAB9A (0.69) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL30461136 | 0.82 | RAB9A (0.69) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL28222646 | 0.82 | RAB9A (0.70) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL12814738 | 0.82 | NPC1 (0.71) | NPC1RAB9ABCHEACHEMAPT | |
| SCHEMBL18883026 | 0.82 | NPC1 (0.69) | NPC1RAB9ABCHEACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367792-A | Quinoxaline diamine type polybenzoxazine foam material and preparation method | UNIV HARBIN ENG | 2016-03-02 | — | — | CN | claimed |
| CN-105367792-A | Quinoxaline diamine type polybenzoxazine foam material and preparation method | UNIV HARBIN ENG | 2016-03-02 | — | — | CN | disclosed |
| US-8592415-B2 | Selective kinase inhibitors | REACTION BIOLOGY CORP. (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2396004-A1 | SELECTIVE KINASE INHIBITORS | Reaction Biology Corp. (US) | 2011-12-21 | — | — | EP | disclosed |
| US-20110071149-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110071149-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2011-03-24 | — | — | US | disclosed |
| WO-2010093808-A1 | SELECTIVE KINASE INHIBITORS | REACTION BIOLOGY CORP. (US) | 2010-08-19 | — | — | WO | disclosed |
| WO-2003007959-A1 | QUINOXALINE DERIVATIVES WHICH HAVE PARP INHIBITORY ACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071149-A1 | SELECTIVE KINASE INHIBITORS | JAK3, JAK1, JAK2 | NPC1 3267/4885RAB9A 1139/4885BCHE 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.