SCHEMBL14634541

SCHEMBL14634541

Cc1cc(S(C)(=O)=O)ncc1OC1CCC(OC2CCN(C)CC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 17/20 0.48
▸ SCN1A P35498 3/20 0.43
▸ SCN8A Q9UQD0 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14634542 1.00 GPR119 (0.48) GPR119SCN1ASCN8A
SCHEMBL12282703 0.82 GPR119 (0.73) GPR119
SCHEMBL2548519 0.82 GPR119 (0.73) GPR119
SCHEMBL14634266 0.79 GPR119 (0.70) GPR119
SCHEMBL14634264 0.79 GPR119 (0.70) GPR119
SCHEMBL14634282 0.77 GPR119 (0.47) GPR119
SCHEMBL14634288 0.77 GPR119 (0.69) GPR119
SCHEMBL14634289 0.77 GPR119 (0.69) GPR119
SCHEMBL14634283 0.77 GPR119 (0.47) GPR119
SCHEMBL14634216 0.76 GPR119 (0.44) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130023494-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2013-01-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023494-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO GPR119, SLC5A2, SLC5A1 GPR119 1/4885SCN1A 788/4885SCN8A 1350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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