Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356467 | 0.87 | ESR2 (0.52) | MEN1KMT2AESR1ESR2ELANE | |
| Ammonia Solution, Strong SCHEMBL20819414 | 0.87 | ELANE (0.42) | MEN1KMT2AELANEGAAMAPT | |
| Phenol SCHEMBL27489897 | 0.86 | TDP1 (0.48) | KMT2AESR1ESR2ELANELTA4H | |
| SCHEMBL10782092 | 0.82 | ELANE (0.44) | MEN1KMT2AESR1ESR2ELANE | |
| SCHEMBL419381 | 0.80 | TDP1 (0.50) | ELANEMAPTKDM4ETDP1 | |
| Hydroquinone SCHEMBL4313659 | 0.80 | ELANE (0.53) | MEN1KMT2AESR1ESR2ELANE | |
| SCHEMBL308379 | 0.80 | ELANE (0.53) | MEN1KMT2AESR1ESR2ELANE | |
| Methacrylic Acid SCHEMBL8512987 | 0.80 | ELANE (0.60) | MEN1KMT2AESR1ESR2ELANE | |
| SCHEMBL24361156 | 0.79 | TPMT (0.44) | ELANECA12CA1CA2CA9 | |
| SCHEMBL17266582 | 0.79 | KMT2A (0.43) | KMT2AKDM4ETDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158578-B2 | Methods for treating neurological deficits | NEUROREPAIR, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110071078-A1 | METHODS FOR TREATING NEUROLOGICAL DEFICITS | REID JAMES STEVEN | 2011-03-24 | — | — | US | disclosed |
| US-7790669-B1 | Methods for treating neurological deficits by intrastriatal administration of transforming growth factor alpha (TGF-α) | NEUROREPAIR, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| EP-0996456-A4 | METHODS FOR TREATING NEUROLOGICAL DEFICITS | UNIV CALIFORNIA (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002049663-A2 | COMPOSITIONS AND METHODS FOR MANIPULATING GLIAL PROGENITOR CELLS AND TREATING NEUROLOGICAL DEFICITS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-27 | — | — | WO | disclosed |
| US-20020004039-A1 | Methods for treating neurological deficits | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007657-A1 | Compositions and methods for manipulating glial progenitor cells and treating neurological deficits | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-12 | — | — | US | disclosed |
| CN-1273534-A | Method for treating neurological deficits | REGENETS OF THE UNIV OF CALIFO (US) | 2000-11-15 | — | — | CN | disclosed |
| EP-0996456-A1 | METHODS FOR TREATING NEUROLOGICAL DEFICITS | The Regents of the University of California (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999006060-A1 | METHODS FOR TREATING NEUROLOGICAL DEFICITS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-02-11 | — | — | WO | disclosed |