Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 9/20 | 0.46 |
| ▸ | JAK1 | P23458 | 9/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23311683 | 0.83 | HDAC2 (0.49) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL14635984 | 0.81 | MEN1 (0.47) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL3925930 | 0.81 | RORC (0.48) | JAK2JAK1HDAC2HDAC1MEN1 | |
| SCHEMBL14635957 | 0.81 | HDAC2 (0.48) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL21606973 | 0.80 | HDAC2 (0.45) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL3356494 | 0.79 | JAK2 (0.46) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL3355538 | 0.78 | RORC (0.48) | JAK2JAK1HDAC2HDAC1MEN1 | |
| SCHEMBL4635533 | 0.78 | JAK2 (0.47) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL22719332 | 0.77 | JAK2 (0.47) | JAK2JAK1HDAC2HDAC1GPR119 | |
| SCHEMBL4634633 | 0.77 | JAK2 (0.45) | JAK2JAK1HDAC2HDAC1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |