Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616620 | 0.89 | MEN1 (0.43) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL1274282 | 0.83 | TP53 (0.55) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL14636212 | 0.82 | ATM (0.41) | ATMALDH1A1FDFT1NPY2RALOX5 | |
| SCHEMBL18245002 | 0.80 | TP53 (0.45) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL3163819 | 0.80 | TP53 (0.45) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL20672072 | 0.79 | TP53 (0.45) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL21537509 | 0.78 | KMT2A (0.42) | MEN1KMT2ATP53POLBATM | |
| SCHEMBL27320984 | 0.78 | NPSR1 (0.38) | MEN1KMT2ATP53POLBALDH1A1 | |
| SCHEMBL20658797 | 0.77 | FDFT1 (0.44) | TP53ATMALDH1A1SMN1; SMN2FDFT1 | |
| SCHEMBL28463297 | 0.76 | FDFT1 (0.46) | MEN1KMT2ATP53POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |