Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616620 | 0.82 | MEN1 (0.43) | ATMFDFT1ALOX5NPY2RALDH1A1 | |
| SCHEMBL14636211 | 0.82 | MEN1 (0.42) | ATMFDFT1ALOX5NPY2RALDH1A1 | |
| SCHEMBL20658797 | 0.81 | FDFT1 (0.44) | ATMFDFT1ALOX5NPY2RALDH1A1 | |
| SCHEMBL3154927 | 0.78 | NPY2R (0.48) | ATMFDFT1ALOX5NPY2RALDH1A1 | |
| SCHEMBL1274282 | 0.78 | TP53 (0.55) | ATMALDH1A1MAPT | |
| SCHEMBL27648278 | 0.77 | ATM (0.43) | ATMFDFT1ALOX5NPY2RALDH1A1 | |
| SCHEMBL27728458 | 0.75 | ATM (0.47) | ATM | |
| SCHEMBL5001045 | 0.75 | ATM (0.47) | ATM | |
| SCHEMBL5390528 | 0.75 | KMO (0.59) | ATMALDH1A1DRD3MAPK1 | |
| SCHEMBL3163819 | 0.75 | TP53 (0.45) | ATMFDFT1ALOX5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |