Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16113010 | 0.81 | TSHR (0.48) | ALDH1A1MAPTKDM4ETDP1PDK4 | |
| SCHEMBL28352494 | 0.79 | MEN1 (0.43) | ALDH1A1MAPTTDP1PDK4MEN1 | |
| SCHEMBL22324761 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTPDK4MEN1KMT2A | |
| SCHEMBL12712665 | 0.74 | PDK4 (0.64) | PDK4 | |
| SCHEMBL20993990 | 0.74 | MAPT (0.50) | ALDH1A1MAPTPDK4MEN1KMT2A | |
| SCHEMBL16114190 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EPDK4MEN1 | |
| SCHEMBL6869489 | 0.73 | MAPT (0.41) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL2390130 | 0.72 | CYP4F2 (0.51) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL17397683 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTPDK4MEN1KMT2A | |
| SCHEMBL4678883 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EPDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |