Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 13/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | UBE2N | P61088 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636004 | 0.89 | CLTC (0.79) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL14636859 | 0.89 | CLTC (0.77) | CLTCHPGDCA12CA1CA2 | |
| SCHEMBL14636024 | 0.88 | CLTC (0.79) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL14636868 | 0.88 | CLTC (0.78) | CLTCHPGDCA12CA1CA2 | |
| SCHEMBL14636558 | 0.85 | CLTC (0.79) | CLTCHPGDCA12CA1CA2 | |
| SCHEMBL14635611 | 0.84 | CA12 (0.69) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL14636234 | 0.83 | CLTC (0.78) | CLTCUBE2NATMCA12CA1 | |
| SCHEMBL28737144 | 0.82 | UBE2N (0.81) | CLTCLMNAHPGDUBE2NATM | |
| SCHEMBL14635627 | 0.78 | CLTC (0.78) | CLTCCA12CA1CA2CA9 | |
| SCHEMBL7848586 | 0.77 | ERCC1 (0.62) | CLTCHPGDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |