Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463663 | 0.86 | KCNH2 (0.59) | KCNH2HRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL1463084 | 0.85 | KCNH2 (0.58) | KCNH2HRH3ALDH1A1RAB9AGABRA1 | |
| SCHEMBL10175817 | 0.83 | RAD51 (0.60) | G6PDCYP11B2CYP11B1CYP17A1CYP19A1 | |
| SCHEMBL1463643 | 0.81 | KCNH2 (0.52) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL1463588 | 0.81 | KCNH2 (0.52) | KCNH2HRH3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1463838 | 0.79 | KCNH2 (0.60) | KCNH2HRH3KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1463978 | 0.79 | KCNH2 (0.60) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL1463880 | 0.79 | KCNH2 (0.60) | KCNH2HRH3KDM4EALDH1A1RAB9A | |
| SCHEMBL1462814 | 0.77 | KCNH2 (0.60) | KCNH2HRH3KDM4EALDH1A1HPGD | |
| SCHEMBL1464928 | 0.76 | CYP3A4 (0.56) | KCNH2HRH3KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | claimed |
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
| EP-2266962-A1 | THE COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | Guangzhou Institute Of Biomedicine And Health, Chinese Academy Of Sciences (CN) | 2010-12-29 | — | — | EP | disclosed |
| CN-101531638-A | Compounds useful as estrogen-related receptor modulators and uses thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | G6PD 342/4885CYP11B2 13/4885CYP11B1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.