SCHEMBL146383

SCHEMBL146383

c1c[nH]c2c(c1)ccc1nccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
LMNA P02545 2/20 0.43
MAPT P10636 3/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 3/20 0.36
DHFR P00374 1/20 0.36
GAA P10253 1/20 0.36
RAD52 P43351 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP19A1 P11511 3/20 0.36
EGFR P00533 1/20 0.35
NR4A2 P43354 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 2/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.33
NCF1 P14598 1/20 0.33
AXL P30530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28071548 0.98 CYP3A4 (0.43) CYP3A4LMNAMAPTKDM4EALDH1A1
SCHEMBL29586567 0.98 CYP3A4 (0.43) CYP3A4LMNAMAPTKDM4EALDH1A1
SCHEMBL27715530 0.98 CYP3A4 (0.43) CYP3A4LMNAMAPTKDM4EALDH1A1
SCHEMBL29190842 0.98 CYP3A4 (0.43) CYP3A4LMNAMAPTKDM4EALDH1A1
SCHEMBL31358268 0.98 CYP3A4 (0.43) CYP3A4LMNAMAPTKDM4EALDH1A1
Hydroquinone SCHEMBL5198905 0.92 MEN1 (0.41) CYP3A4LMNAMAPTKDM4EALDH1A1
Acetonitrile SCHEMBL10471610 0.91 CYP3A4 (0.38) CYP3A4LMNAMAPTKDM4EALDH1A1
Guanidine SCHEMBL7619937 0.91 CYP3A4 (0.41) CYP3A4LMNAMAPTKDM4EALDH1A1
Quinoline SCHEMBL10490755 0.91 ALDH1A1 (0.52) CYP3A4LMNAMAPTKDM4EALDH1A1
Benzoquinone SCHEMBL27411699 0.91 CYP3A4 (0.38) CYP3A4LMNAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2054 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185329-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 EP claimed
US-20260076935-A1 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2026-03-19 US claimed
EP-4683625-A2 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE The Trustees Of Columbia University In The City Of New York (US) 2026-01-28 EP claimed
US-20250389687-A1 METHOD OF FORMING ELECTRICAL SIGNAL SENSOR NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) 2025-12-25 US claimed
CN-119868385-A Application of pyrroloquinoline-polyamine analogue combined with doxorubicin in preparation of antitumor drugs 河南大学 2025-04-25 CN claimed
WO-2025058667-A2 PREVENTION AND TREATMENT OF CONDITIONS USING ETHYL PYRUVATE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-03-20 WO claimed
EP-3523639-B1 DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME HOFFMANN LA ROCHE (CH) 2024-12-18 EP claimed
CN-118915405-A Low-corrosion chip photoresist stripping liquid, and preparation method and application thereof 浙江奥首材料科技有限公司 2024-11-08 CN claimed
CN-118872863-A NMN and citrulline-based dietary supplement and preparation method thereof 杭州凯创生物科技有限公司 2024-11-01 CN claimed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN claimed
US-6200773-B1 QUANTITATIVE ANANLYSIS OF HEMOGLOBIN LIFESCAN, INC. 2001-03-13 US claimed
WO-2000075139-A2 BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2000-12-14 WO claimed
EP-0990706-A1 Diagnostics based on tetrazolium compounds LIFESCAN, INC. (US) 2000-04-05 EP claimed
US-5792630-A USING AN ACETOBACTER STRAIN MUTANT; CULTURES; EFFICIENCY BIO-POLYMER RESEARCH CO., LTD. (JP) 1998-08-11 US claimed
EP-0390135-B1 Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same OTSUKA PHARMA CO LTD (JP) 1996-06-05 EP claimed
US-5185337-A Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-02-09 US claimed
EP-0429333-A1 Process for producing oxazopyrroloquinolines, novel oxazopyrroloquinolines, and use of oxazopyrroloquinolines MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-05-29 EP claimed
CN-1047081-A Antiseptic-germicide is with the manufacture method of composition and wherein used pyrroloquinoline derivative OTSUKA PHARMA CO LTD (JP) 1990-11-21 CN claimed
EP-0390135-A1 Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-10-03 EP claimed
EP-0029286-A1 Pyrrolo(3,4-c)quinoline derivatives, processes therefor, and pharmaceutical compositions ICI AMERICAS INC. (US) 1981-05-27 EP claimed