Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.88 |
| ▸ | APP | P05067 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 2/20 | 0.72 |
| ▸ | HTR2C | P28335 | 2/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.72 |
| ▸ | HTR6 | P50406 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terrestribisamide SCHEMBL10735557 | 0.94 | TYR (1.00) | TYRAPPACHEHPGDTRPV1 | |
| Terrestribisamide SCHEMBL30382198 | 0.94 | TYR (1.00) | TYRAPPACHEHPGDTRPV1 | |
| Terrestribisamide SCHEMBL31278144 | 0.94 | TYR (1.00) | TYRAPPACHEHPGDTRPV1 | |
| SCHEMBL8847848 | 0.90 | HTR1A (0.76) | TYRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL8847845 | 0.90 | HTR1A (0.76) | TYRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL30819192 | 0.89 | TYR (0.86) | TYRACHETRPV1 | |
| SCHEMBL29280387 | 0.89 | TYR (0.86) | TYRACHETRPV1 | |
| SCHEMBL31297163 | 0.89 | TYR (0.90) | TYRAPPACHEHPGDTRPV1 | |
| SCHEMBL29664123 | 0.89 | TYR (0.90) | TYRAPPACHEHPGDTRPV1 | |
| SCHEMBL1675877 | 0.88 | TYR (0.88) | TYRAPPACHEHPGDTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127316-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | NEW YORK UNIVERSITY | 2014-05-08 | — | — | US | disclosed |
| WO-2013012477-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127316-A1 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF | EP300, HDAC1, HDAC8 | TYR 1323/4885APP 1017/4885HTR1A 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.