Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3773525 | 0.75 | CYP2D6 (0.36) | KMT2AMEN1NPY5R | |
| SCHEMBL30885716 | 0.73 | KMT2A (0.50) | KMT2AMEN1NOTUML3MBTL1TSHR | |
| SCHEMBL1222479 | 0.72 | NPY5R (0.47) | NPY5R | |
| SCHEMBL14639364 | 0.72 | NOTUM (0.43) | KMT2AMEN1NOTUMTSHRHSD11B1 | |
| SCHEMBL29391669 | 0.72 | MAOA (0.48) | NOTUM | |
| SCHEMBL17383970 | 0.72 | MAOA (0.48) | NOTUM | |
| SCHEMBL5578847 | 0.70 | MAPT (0.50) | KMT2AMEN1L3MBTL1HSD11B1 | |
| SCHEMBL14062149 | 0.70 | NOTUM (0.44) | KMT2AMEN1NOTUMHSD11B1 | |
| SCHEMBL29791451 | 0.70 | NOTUM (0.44) | KMT2AMEN1NOTUMHSD11B1 | |
| SCHEMBL1222975 | 0.70 | NAMPT (0.40) | NPY5RHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013013031-A1 | PYRIDAZINO [4, 5 -D] PYRIMIDIN- (6H) -ONE INHIBITORS OF WEE - 1 KINASE | ABBVIE INC. (US) | 2013-01-24 | — | — | WO | disclosed |