Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642224 | 0.88 | SLC6A4 (0.46) | MEN1KMT2APOLBHRH3ALDH1A1 | |
| SCHEMBL641547 | 0.87 | KMT2A (0.46) | MEN1KMT2APOLBKDM4EHRH3 | |
| SCHEMBL14639764 | 0.85 | MEN1 (0.43) | MEN1KMT2APOLBHRH3MAPK14 | |
| SCHEMBL14639763 | 0.83 | NAMPT (0.42) | MEN1KMT2APOLBKDM4ENAMPT | |
| SCHEMBL642465 | 0.74 | SLC6A4 (0.52) | MEN1KMT2APOLBKDM4EHRH3 | |
| SCHEMBL9965443 | 0.73 | SLC6A4 (0.48) | MEN1KMT2APOLBHRH3ALDH1A1 | |
| SCHEMBL641796 | 0.73 | SLC6A4 (0.50) | MEN1KMT2APOLBKDM4EHRH3 | |
| SCHEMBL640921 | 0.73 | CCR8 (0.57) | MEN1KMT2APOLBHRH3DRD4 | |
| SCHEMBL641293 | 0.71 | SLC6A4 (0.47) | MEN1KMT2APOLBKDM4EHRH3 | |
| SCHEMBL9965414 | 0.70 | KMT2A (0.49) | MEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |