Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14639763 | 0.89 | NAMPT (0.42) | MEN1KMT2APOLBGHSREPHX2 | |
| SCHEMBL641796 | 0.88 | SLC6A4 (0.50) | MEN1KMT2APOLBGHSREPHX2 | |
| SCHEMBL14639726 | 0.85 | MEN1 (0.43) | MEN1KMT2APOLBMAPK14DRD4 | |
| SCHEMBL641293 | 0.77 | SLC6A4 (0.47) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL642465 | 0.77 | SLC6A4 (0.52) | MEN1KMT2APOLBBCHEACHE | |
| SCHEMBL13848430 | 0.75 | DRD4 (0.57) | MEN1KMT2APOLBGHSRBCHE | |
| SCHEMBL9965443 | 0.74 | SLC6A4 (0.48) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL640921 | 0.73 | CCR8 (0.57) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL642224 | 0.73 | SLC6A4 (0.46) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL5072840 | 0.73 | MEN1 (0.47) | MEN1KMT2APOLBBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |