Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13248372 | 0.83 | BCHE (0.52) | HRH3MAPTPOLBAPEX1TDP1 | |
| SCHEMBL3113481 | 0.82 | MAPT (0.64) | HRH3MAPTMCHR1 | |
| SCHEMBL15308539 | 0.81 | PYCR1 (0.56) | HRH3POLBAPEX1TDP1PYCR1 | |
| SCHEMBL20287494 | 0.80 | HRH3 (0.72) | HRH3MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL995037 | 0.80 | TAAR1 (0.43) | HRH3MAPTPYCR1TAAR1ALDH1A1 | |
| SCHEMBL14884505 | 0.80 | BCHE (0.49) | HRH3MAPTMCHR1ALDH1A1 | |
| SCHEMBL27258713 | 0.79 | POLB (0.51) | HRH3POLBAPEX1TDP1PYCR1 | |
| SCHEMBL6264177 | 0.78 | HTT (0.54) | HRH3MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12894414 | 0.78 | HRH3 (0.69) | HRH3MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13078725 | 0.78 | HRH3 (0.69) | HRH3MAPTCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006547-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |