Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30155 | 1.00 | LMNA (0.32) | LMNACYP2C9GBA1CHRM2CHRM1 | |
| SCHEMBL12217040 | 0.90 | LMNA (0.33) | LMNACYP2C9GBA1CHRM2CHRM1 | |
| SCHEMBL30203 | 0.81 | CYP2C9 (0.32) | CYP2C9GBA1 | |
| SCHEMBL13900980 | 0.81 | CYP2C9 (0.32) | CYP2C9GBA1 | |
| SCHEMBL14473283 | 0.81 | CYP2C9 (0.32) | CYP2C9GBA1 | |
| SCHEMBL16800305 | 0.80 | GBA1 (0.33) | GBA1 | |
| SCHEMBL172113 | 0.79 | GBA1 (0.30) | GBA1 | |
| SCHEMBL3104581 | 0.79 | GBA1 (0.30) | GBA1 | |
| SCHEMBL10035795 | 0.77 | FUCA1 (0.33) | — | |
| SCHEMBL8863482 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310474-B1 | Fluorinated biphenyl compounds and their use in liquid crystal compositions | MERCK PATENT GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |