Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677620 | 0.85 | SMN1; SMN2 (0.40) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1677828 | 0.85 | SMN1; SMN2 (0.40) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1677618 | 0.85 | SMN1; SMN2 (0.40) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14419716 | 0.85 | ALDH1A1 (0.35) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14640175 | 0.82 | CNR2 (0.31) | CNR2CNR1MEN1ALDH1A1GAA | |
| SCHEMBL14640151 | 0.82 | ALDH1A1 (0.33) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14640138 | 0.82 | ALDH1A1 (0.33) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL13635234 | 0.79 | ALDH1A1 (0.33) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14582631 | 0.77 | CNR2 (0.37) | CNR2CNR1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL14582633 | 0.76 | ALDH1A1 (0.33) | CNR2CNR1MEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743885-A2 | TNF-Alpha Produktion Hemmer zur Behandlung von Autoimmunerkrankungen | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2007-01-17 | — | — | EP | disclosed |