Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266524 | 0.85 | PTGDR2 (0.49) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| SCHEMBL12896972 | 0.85 | PTGDR2 (0.49) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| SCHEMBL1093945 | 0.83 | HTR2C (0.61) | PTGDR2PTGDRHTR2AHTR2C | |
| SCHEMBL24252872 | 0.83 | PTGDR2 (0.46) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| SCHEMBL12896664 | 0.82 | OPRM1 (0.53) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1266139 | 0.82 | HTR2C (0.62) | PTGDR2PTGDRHTR2AHTR2C | |
| SCHEMBL10534970 | 0.81 | PTGDR2 (0.60) | PTGDR2PTGDRTSHRL3MBTL1HTR2A | |
| SCHEMBL4572970 | 0.81 | PTGDR2 (0.49) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| SCHEMBL4888059 | 0.80 | PTGDR2 (0.64) | PTGDR2PTGDRPTGER2MEN1KMT2A | |
| SCHEMBL11819421 | 0.79 | HTR2A (0.53) | PTGDR2PTGDRMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006547-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |