Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624342 | 0.83 | PLA2G1B (0.43) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL27449911 | 0.82 | DNM1 (0.43) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL27449909 | 0.82 | DNM1 (0.43) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL27449951 | 0.82 | DNM1 (0.43) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL27449872 | 0.82 | DNM1 (0.43) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL9400807 | 0.81 | SPHK1 (0.38) | SPHK1OPRM1DNM1TP53CYP2D6 | |
| SCHEMBL10674908 | 0.79 | DNM1 (0.48) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL5539887 | 0.79 | DNM1 (0.48) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL28601890 | 0.79 | DNM1 (0.48) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 | |
| SCHEMBL5544687 | 0.79 | DNM1 (0.48) | SPHK1OPRM1PLA2G1BPLA2G2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002635-A2 | C-LINKED CYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |