Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094537 | 0.84 | CNR1 (0.57) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL27353884 | 0.84 | ESRRG (0.54) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL17131842 | 0.84 | HPGD (0.55) | CNR1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL25342705 | 0.81 | CYP1A2 (0.58) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL4582082 | 0.79 | TAAR1 (0.65) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL5574769 | 0.78 | LMNA (0.66) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL1008891 | 0.78 | KDM4E (0.70) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL8581580 | 0.78 | IDO1 (0.68) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL25344865 | 0.78 | CYP1A2 (0.54) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL5681870 | 0.76 | CA12 (0.75) | CNR1CYP1A2CYP2D6CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011290-A1 | Bronchorelaxing agents based on indol- and isoquinoline derivatives | RESPIRATORIUS AB (SE) | 2007-01-25 | — | — | WO | disclosed |